Hypersensitivity. Temporary enlargement of pupils. Overuse may cause more redness of the eyes. Remove contact lens before use. Heart disease, high BP, narrow-angle glaucoma or urinary difficulty. Childn <6 yr.
Increased pressure effects w/ maprotiline or TCA. Possibility of severe hypertensive reaction w/ MAOI. Increased IOP w/ agents that stimulate α1- & α2-adrenergic receptors. Urinary difficulty or worsen smooth muscle contraction in the bladder neck w/ α1-adrenergic receptor stimulators. Possibility of severe hypertensive reaction w/ stimulation of β1-adrenergic receptors. Slight increases in blood glucose conc in patients w/ DM.
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